产品货号：
Z17726
中文名称：
HDAC3抗体
英文名称：
Anti-HDAC3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDAC3 Antibody |
| 指标别名 | HD3;HDAC3;histone deacetylase 3;RPD3;RPD3 2;SMAP45 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | HDAC3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human HDAC3 recombinant protein (Position:M1-I428). |
| 实际分子量 | 49KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HDAC3 (HISTONE DEACETYLASE 3) is a member of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC3 gene.The HDAC3 gene is mapped to 5q31.3.HDAC3 has histone deacetylase activity and represses transcription when tethered to a promoter.It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.The protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.And this gene is regarded as a potential tumor suppressor gene.HDAC3 has an open reading frame of 428 amino acids and shares 53% amino acid identity with HDAC1 and 52% with HDAC2.The catalytic domain of HDAC4 interacts with HDAC3 via the transcriptional corepressor NCOR2.All experimental conditions leading to the suppression of HDAC4 binding to NCOR2 and to HDAC3 resulted in loss of enzymatic activity associated with HDAC4.HDAC3 recruitment to the genome displays a circadian rhythm in mouse liver. |
| Uniprot ID | O15379 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
相关搜索：HDAC3抗体，HDAC3多抗，Anti-HDAC3 Antibody